Anxiety and depression can feel overwhelming. These struggles affect our thoughts, emotions, and relationships—and often, our faith. But the Bible offers more than just comfort; it offers hope. God’s Word speaks directly to our pain, gently guiding us toward peace, healing, and strength.
Whether you’re personally experiencing anxiety or depression, or walking with someone who is, these Bible verses about anxiety and depression will remind you that you are not alone. God is near to the brokenhearted, and He cares deeply about your emotional well-being.
35 Bible Verses About Anxiety and Depression
1. Philippians 4:6
Do not be anxious about anything, but in everything by prayer and supplication with thanksgiving let your requests be made known to God.
Explanation:
This verse encourages us to turn our worries into prayers. God invites us to bring everything to Him, no matter how heavy.
2. 1 Peter 5:7
Casting all your anxieties on him, because he cares for you.
Explanation:
God doesn’t just tolerate our fears—He welcomes them. This verse reminds us that He cares personally and wants to carry our burdens.
3. Psalm 34:17-18
When the righteous cry for help, the Lord hears and delivers them out of all their troubles. The Lord is near to the brokenhearted and saves the crushed in spirit.
Explanation:
God listens and stays close during pain. He doesn’t leave us in the dark moments but walks with us through them.
4. Matthew 11:28-30
Come to me, all who labor and are heavy laden, and I will give you rest…
Explanation:
Jesus offers true rest for the weary. His invitation is open to anyone feeling overwhelmed.
5. Isaiah 41:10
Fear not, for I am with you; be not dismayed, for I am your God…
Explanation:
This powerful promise reminds us that God’s presence is a constant source of courage and strength.
6. John 14:27
Peace I leave with you; my peace I give to you. Not as the world gives do I give to you…
Explanation:
Jesus gives a kind of peace that goes deeper than circumstances. It calms the soul even in storms.
7. Psalm 42:11
Why are you cast down, O my soul, and why are you in turmoil within me? Hope in God…
Explanation:
This verse captures the inner dialogue of depression but redirects the heart toward hope and trust in God.
8. Romans 8:38-39
For I am sure that neither death nor life… will be able to separate us from the love of God…
Explanation:
Even in our darkest valleys, God’s love remains. Nothing—not even depression—can take that away.
9. Joshua 1:9
Have I not commanded you? Be strong and courageous… for the Lord your God is with you wherever you go.
Explanation:
This encouragement is a reminder that God’s presence is with us always, giving strength when fear rises.
10. Proverbs 12:25
Anxiety in a man’s heart weighs him down, but a good word makes him glad.
Explanation:
God knows how anxiety affects us—and how healing kind words can be. His Word is the good word we need.
11. Psalm 23:4
Even though I walk through the valley of the shadow of death, I will fear no evil…
Explanation:
This classic verse is a promise of God’s presence and protection, even in our darkest days.
12. Isaiah 26:3
You keep him in perfect peace whose mind is stayed on you, because he trusts in you.
Explanation:
Peace comes when we fix our thoughts on God. Trusting Him brings calmness that anxiety can’t shake.
13. 2 Corinthians 1:3-4
Blessed be… the God of all comfort, who comforts us in all our affliction…
Explanation:
God not only comforts us but equips us to comfort others through what we’ve experienced.
14. Psalm 55:22
Cast your burden on the Lord, and he will sustain you…
Explanation:
We’re not meant to carry everything ourselves. God invites us to unload our worries onto Him.
15. Matthew 6:34
Therefore do not be anxious about tomorrow, for tomorrow will be anxious for itself…
Explanation:
This verse helps us stay present and trust God one day at a time, without being overwhelmed by the future.
16. Lamentations 3:22-23
The steadfast love of the Lord never ceases… great is your faithfulness.
Explanation:
Even in sorrow, God’s love is constant. His mercies are new every morning.
17. Psalm 94:19
When the cares of my heart are many, your consolations cheer my soul.
Explanation:
God’s comfort is real and emotional. He lifts us when our hearts feel crushed.
18. Isaiah 43:2
When you pass through the waters, I will be with you…
Explanation:
God doesn’t promise we won’t face trouble, but He promises we’ll never face it alone.
19. 2 Timothy 1:7
For God gave us a spirit not of fear but of power and love and self-control.
Explanation:
Fear is not from God. He fills us with strength and a sound mind, even when our emotions feel shaky.
20. Psalm 40:1-2
I waited patiently for the Lord; he inclined to me and heard my cry…
Explanation:
God hears our cries and lifts us out of emotional pits. He is faithful to respond.
21. Hebrews 13:5
I will never leave you nor forsake you.
Explanation:
A simple, strong promise. God is always with us, even when we feel alone.
22. Nahum 1:7
The Lord is good, a stronghold in the day of trouble…
Explanation:
God is our safe place when we’re overwhelmed. His goodness is a refuge.
23. Psalm 31:24
Be strong, and let your heart take courage, all you who wait for the Lord!
Explanation:
Encouragement to hold on. Strength rises as we wait and hope in God.
24. Romans 15:13
May the God of hope fill you with all joy and peace in believing…
Explanation:
Hope and peace come through faith. Even in hard times, God can fill us with joy.
25. Isaiah 40:31
But they who wait for the Lord shall renew their strength…
Explanation:
Waiting on God isn’t passive—it leads to renewal, even when we feel drained.
26. Psalm 27:14
Wait for the Lord; be strong, and let your heart take courage…
Explanation:
This is a reminder to trust God’s timing. Courage grows as we stay close to Him.
27. John 16:33
In the world you will have tribulation. But take heart; I have overcome the world.
Explanation:
Jesus acknowledges trouble but promises victory. He’s overcome what we fear most.
28. Colossians 3:15
And let the peace of Christ rule in your hearts…
Explanation:
We’re invited to let God’s peace take control, replacing fear and confusion.
29. Psalm 147:3
He heals the brokenhearted and binds up their wounds.
Explanation:
God is the ultimate Healer—not just physically but emotionally and spiritually.
30. Zephaniah 3:17
The Lord your God is in your midst… he will quiet you by his love…
Explanation:
God’s presence and love bring peace to an anxious heart. He sings over us with joy.
31. Ecclesiastes 3:1,4
For everything there is a season… a time to weep, and a time to laugh…
Explanation:
This reminds us that sadness is part of life’s rhythm—but it’s not the end. Joy will return.
32. Galatians 6:2
Bear one another’s burdens, and so fulfill the law of Christ.
Explanation:
We are called to support each other. No one has to carry their pain alone.
33. Proverbs 3:5-6
Trust in the Lord with all your heart, and do not lean on your own understanding…
Explanation:
When life doesn’t make sense, trust God anyway. He will guide you through the fog.
34. Revelation 21:4
He will wipe away every tear from their eyes…
Explanation:
This is the ultimate hope—one day, all pain, anxiety, and depression will be gone forever.
35. Psalm 30:5
Weeping may tarry for the night, but joy comes with the morning.
Explanation:
Seasons of sadness don’t last forever. God promises that joy will rise again.
Final Thoughts: There Is Hope and Healing in God’s Word
Anxiety and depression can feel isolating, but Scripture reminds us again and again that we are not alone. These Bible verses about anxiety and depression offer real comfort and lasting hope. God sees you, hears you, and loves you deeply—right where you are.
Let these verses remind you to breathe, to hope, and to draw close to the One who promises peace. Keep seeking Him in prayer, and don’t hesitate to reach out to others when you need help.
What verse speaks to you the most?
Share your favorite Scriptures, experiences, or reflections in the comments. Let’s encourage one another in faith and healing.